Check for the presence of V1 signature scheme with a minimum SDK version targeting < Android 7.0 - If this is found, the app is vulnerable to the Janus vulnerability (CVE-2017-13156). See https://www.guardsquare.com/en/blog/new-android-vulnerability-allows-attackers-modify-apps-without-affecting-their-signatures for more information.
APK's support 3 signature schemes:
Version 1 (JAR signing)
How to check:
install apksigner
(apt install apksigner) and run:
apksigner verif -v APK_name