LSASS running as RunasPPL

ERROR kuhl_m_sekurlsa_acquireLSA ; Handle on memory (0x00000005)

See RunAsPPL Page

No sufficient privileges- SeDebugPrivilege is disabled

mimikatz(commandline) # PRIVILEGE::Debug
ERROR kuhl_m_privilege_simple ; RtlAdjustPrivilege (20) c0000061

means that you do not have the require privilege to run the command. Try running Mimikatz as an administrator.